Endocrine Abstracts

Low glycaemic index (GI) diet and gut hormones such as glucagon-like peptide 1 (GLP-1) and peptide YY (PYY) have been shown independently to reduce appetite. However, the direct relationship between a single meal of low or high GI and the levels of these hormones has not been studied. In this study we looked at the short term effects of a single low or high GI meal on plasma levels of GLP-1, PYY and insulin.King’s College London’s research ethi...

A 50 year old lady was referred with a two year history of recurrent spontaneous hypoglycaemic episodes. She had put on a stone in weight over this time period. She was otherwise fit and well and took no regular medications. She had a past medical history of treated melanoma. None of her family members had diabetes mellitus. Neither she nor her husband worked in a healthcare setting but her daughter was a district nurse. Prior to referral, she had a normal short synacthen test...